GE Sepax C-Pro Cell Processing System

GE Sepax C-Pro Cell Processing System

**This unit has been tested to specifications. The unit has broken damage at the bottom back of the screen(Does not affect functionality). Buyer can expect a working system. See photos for further details.

The Sepax C-Pro Cell Processing System, which is comprised of the instrument, Sepax C-Pro protocol software, and kits, allows you to combine multiple processing steps in a versatile manner. These steps include but are not limited to enrichment, magnetic bead incubation, spin osculation, concentration, washing, dilution, and splitting. Support your requirements and system implementation. Automated and functionally closed system to support GMP compliance. Simplify your operations. Compact design and user-friendly interface minimize your space and resource requirements. Maintain flexibility. Sepax C-Pro is a multipurpose solution allowing you to perform diverse and dedicated applications. Simplify record-keeping. Sepax C-Pro can transmit instrument data and alarms for remote monitoring or for incorporation into a Chronicle ESOP. Keep operations running smoothly. Integrate with Chronicle manufacturing automation software to monitor all connected instruments (Sepax C Pro and others) and manage service records.

The Sepax C-Pro Cell Processing Instrument has been used to prepare CAR T cells, natural killer cells (NK cells), and other cell types. Sepax C-Pro can be part of a robust CAR T cell manufacturing workflow that is adaptable for cGMP compliance in production of clinically relevant doses. In a natural killer cell manufacturing workflow, the Sepax C-Pro system was used with Bead Wash C-Pro protocol software to functionally close and automate incubation with magnetic beads for CD3 depletion and CD56 selection. These steps were included in a workflow with Xeno-free expansion that generated 1 × 10⁹ primary human NK cells and can be adapted for GMP compliance. Instrument flexibility. In combination with the appropriate protocol software and single-use kit, the instrument can perform the following operations:

• Concentrate cells from fresh apheresis product via plasma depletion.
• Concentrate cells and remove platelets from fresh apheresis units.
• Incubate magnetic beads onto the cell fractions obtained from apheresis units sequence concentration, platelet depletion, bead incubation, and washing.
• Enrich mononuclear cells fraction via a density gradient medium.
• Concentrate, wash, and transduce isolated cells by spin osculation.
• Dilute, concentrate, and wash fresh or frozen cellular product.
• Dilute and split cellular products into multiple bags for accurate dosing.
• Touch screen with Stopcock manifold. 
• Optical and pressure sensors with Hooks and pole.
• USB and ethernet ports.

Specifications