Thermo Scientific TSQ Vantage Mass Spectrometer

Thermo Scientific TSQ Vantage Mass Spectrometer

 ***This unit was tested to specifications. TSQ Vantage powers on and able to connect to software. Unit has slight wear from normal use. System will need to be validated/calibrated to ensure accurate results. Inquire about system validation for an additional cost. (Ion source not included). See photos for details. 

The Thermo Scientific TSQ Vantage Mass Spectrometer offers consistent, specific and reproducible results at low levels of quantitation. Whether analyzing small molecules or biomolecules, the Thermo Scientific TSQ Vantage Mass Spectrometer provides superior assay precision and accuracy with the lowest chemical noise. 

• Delivers more ions to the detector due to advances in the ion source and collision cell designs.
• Patented G2 ion optics - provides superior assay precision and accuracy  with the lowest chemical noise. 
• Greater desolvation characteristics with HESI-II design for improved high flow performance(> 1mL/min) 
• HyperQuad™ quadrupole mass filters to reduce chemical noise (H-SRM)
  Run repeat analysis of incurred samples at any time, due to necessary sensitivity and easy-to-use, reliable interface 
• Improved heater design for better desolvation at higher flow rates
• Cleaner nozzle profile improves electrostatic fields which results in a single position that works for most flow rates.
• Collision cell design allows SRM scans performed at the fastest possible scan speeds, while ensuring zero cross-talk by accelerating the removal of product ions from within the collision cell before the next precursor ion is delivered. 
• S-Lens captures the expanding ion-rich gas plume and efficiently focuses the ions in a tight beam into the high vacuum region. 
  
  

Inspired innovation are two words that best describe the TSQ Vantage, a triple quadrupole destined to challenge conventional thinking. Its patented G2 ion optics deliver more ions to the detector due to advances in the ion source and collision cell designs. Greater desolvation characteristics of the new HESI-II design provide improved high flow performance
(> 1mL/min) and the TSQ Vantage comes standard with HyperQuad™ quadrupole mass filters, which reduce chemical noise (H-SRM). The benefit of more signal and less noise is assurance that your data will withstand the harshest scrutiny. The TSQ Vantage gives you the confidence to run repeat analysis of incurred samples at any time, because you know you have sensitivity in reserve and a dependable robust interface that is easy to use.

Quantify small molecules, peptides, biosimilars, and biologics using the Thermo Scientific TSQ Vantage triple quadrupole mass spectrometer. With high sensitivity and low noise, the TSQ Vantage system delivers high assay precision and accuracy for a range of bioanalytical, clinical research, environmental, and proteomics applications.

The TSQ Vantage meets the rigorous demands of supporting validated methods required for GLP. Whether you are analyzing
small molecules or biomolecules, the TSQ Vantage gives you consistent, specific and reproducible results at amazingly low
levels of quantitation.

Features:

• Thermo Scientific™ Ion Max™ ion source with HESI-II probe and Thermo Scientific™ HyperQuad™ mass filter reduce noise and increase sensitivity, enhancing quantitative performance
• Quantitation-enhanced data-dependent MS/MS (QED-MS/MS) provides simultaneous compound confirmation and quantification
• High-resolution selected reaction monitoring (H-SRM) enables quantification of many compounds in a single run
• Zero-cross-talk collision cell eliminates false positives
• Self-cleaning Ion Max source and automatic source recognition simplify operation and increase reliability
• Optional 3000 Da mass range, which also includes higher mass resolution and higher-resolution precursor selection, improves analysis of peptides, polysaccharides, intact proteins, and oligo nucleotides
• Optional accurate mass (AM) capability provides a higher degree of confidence in compound identification
  
  

Manufacturer's Specifications:

Mass Range

• m/z 10-1500 daltons (Da)
  

Resolution

• 7500 (FWHM) at m/z 508 of polytyrosine
•  Resolution is continuously adjustable to better than 0.1 Da peak width (FWHM) across the entire mass range

Mass Stability

• Mass assignment will be within ±0.050 Da over a 24-hour period. The laboratory room temperature must be maintained between 15-27°C (59-81°F). The optimum temperature of operation is between 18-21°C (65-70°F). The room temperature may not change by more than 5°C (9°F) during this period

Gas

• Collision gas: 99.995% pure Argon 
• Collision gas supply pressure: 135 ±70 kPa (20 ±10 psig) 
• Sheath/aux/sweep gas: 99% pure Nitrogen 
• Sheath/aux/sweep gas supply pressure: 690 ±140 kPa (100 ±20 psig) 
• Maximum sheath gas consumption: ~ 20 L/min