Novasep ProChrom LC80.600.VE100 Dynamic Axial Compression Column
***Unit is in excellent condition with slight wear from normal use. Buyer can expect the same item pictured with 30-day warranty. See photos for details.
Prochrom® Columns world leading HPLC columns for pharmaceutical applications
With a strong track record in developing, using and supplying preparative HPLC solutions, Novasep offers state-of-the-art
Prochrom® HPLC columns for intermediate purification and polishing of APIs, biologics and other small molecules, from development to large-scale commercial phase.
- A range of standard columns with internal diameters from 50 mm up to 1.2 m
- Adjustable column bed length from 350 mm to 450 mm
- Operation at high pressure – up to 100 bar
- Thermostated jacket for temperature control
- Optimum column performance with easy scale-up of your processes
- Robustness-Novasep Prochrom® High Pressure columns are acclaimed for their durability
- Prochrom columns installed in the early 1980s are still in use
- Many features and accessories for fast and easy operation of columns ensure that a single operator can safely use Prochrom® DAC columns up to 1.6 m diameter
- Column packing by Dynamic Axial Compression Principle
- Maintain your stationary phase performance with Dynamic Axial Compression (DAC) technology
| Column Name |
Column Diameter (Mm) |
Maximum Bed Length (Mm) |
Prochrom Hypersep Systems |
Typical Flow-Rate (L/H) |
Max. Operating Pressure (Bar) |
| LC50.500.VE100 |
50 |
300 |
Lab I |
06-12 |
100 |
| LC80.600.VE100 |
80 |
350 |
Lab I |
15-30 |
100 |
| LC100.650.VE100 |
100 |
350 |
Lab II |
24-48 |
100 |
| LC110.650.VE100 |
110 |
350 |
Lab II |
30-60 |
100 |
| LC150.700.VE100 |
150 |
400 |
Lab II / S |
55-110 |
100 |
| LC200.700.VE100 |
200 |
400 |
S/M |
100/200 |
100 |
| LC300.700.VE100 |
300 |
400 |
M/L |
225/450 |
100 |
| LC450.700.VE100 |
450 |
400 |
M/L |
400/800 |
100 |
| LC590.700.VE70 |
590 |
400 |
L / XL |
900/1800 |
70 |
| LC800.700.VE70 |
800 |
400 |
XL |
1600/3200 |
70 |
| LC1000.700.VE70 |
1000 |
400 |
XL |
2500/5000 |
70 |
| LC1200.700.VE70 |
1200 |
400 |
XL |
3600/7200 |
70 |
Prochrom DAC dynamic axial compression column (LC80) is designed to operate under cGMP conditions. Any type of packing can be used to fill the compression column. At the same time, the compression column will provide appropriate protective pressure to avoid damage to the packing particles. Almost all commonly used chromatography solvents can be used for safe and effective separation operations.
Dynamic Axial Compression (DAC)
Provides the optimum packed bed density and stability, thereby ensuring optimum separation efficiency and consistent performance for an extended period of time. The column includes a movable piston attached to a hydraulic jack. The piston is used to pack and unpack the column, and keep the stationary phase under dynamic compression, ensuring the highest efficiency and bed stability at any scale. Together with Novasep’s unique flow distribution system, and DAC technology enables us to guarantee the same performance (plates/meter, asymmetry) from 50 mm ID to 1.6 m ID.
For applications requiring the use of soft and/or fragile packing materials, the concept of smart piston has been developed and patented, preventing the crushing of particles or gels. The piston is automatically adjusted with the swelling or shrinkage of the stationary phase to maintain a constant compression over time.
- Best-in-Class separation with highest HETP
- Smart piston to maintain constant pressure
- Optimized packing technology with advanced flow distributors ensure highest efficiency
- Guaranteed scale up and Performance
