Single Use, TFF Tank Cart Mixer Mobius Flexready Smart System MSP55137103

Millipore Smart TFF, Single Use TFF Skid Mobius FlexReady Smart System MSP551371

**Pre-owned in excellent condition. See pictures for details** Comes with 30 day warranty. FOB: FRANKLIN, MA

• 100% single-use flowpath—Smart Flexware® single-use assemblies provide ease-of-use, robust reproducibility, and elimination of carryover from previous batches
• Closed mode of operation is possible with specifically designed flowpath and equipment, allowing to reduce contamination risk while increasing flexibility and efficiency
• Fully automated—Enables you to easily and consistently produce clinical- and preclinical-scale quantities of high-value drug products. The system is compatible with Bio4C™ Orchestrator Software, allowing you to monitor and visualize your bioprocess from anywhere.
• User-friendly—The system shares common elements, such as software, design, and maintenance components with our other systems, making training and validation easier across scales and applications
• Services—Comprehensive services ensure rapid implementation and optimized performance
• Supports industry-leading devices, including Pellicon® cassettes for functionally closed processing and Pellicon® capsules for fully closed processing

MD Millipore, the life science division of Merck KGaA of Darmstadt, Germany, has launched the Mobius® FlexReady Solution with Smart Flexware® Assemblies for tangential flow filtration (TFF). The fully automated system is ready to implement and features scalable, industry-leading filtration technologies for unmatched performance and operational flexibility.

Unlike traditional single-use processing systems, this modular system is quick and easy to set up, providing the ability to switch from TFF to Chromatography with a minimum number of component changes, making it ideal for pilot plants and CMOs that have rapidly changing demands.

The system is suited for a wide range of concentration and diafiltration processes. In addition to the feed pump and retentate valve control loops, the system also includes an automated flow control valve on the filtrate line to enable open ultrafiltration and microfiltration operations, increasing the overall flexibility for clinical development and manufacturing facilities.

A variety of recycle vessel configurations are available with the Mobius® FlexReady Solution to provide maximum process capability. In addition to different vessel volumes, users can select a plastic carrier or a double-jacketed stainless steel carrier, depending on whether or not temperature control is required. All recycle vessels come with integrated load cells, mixer, and temperature sensor, and have been designed such that the containers can be easily and accurately installed by a single operator.

"With the introduction of this fully automated Mobius® single-use TFF system, we are able to provide our customers that require a high level of processing control a choice for performing their Ultrafiltration/diafiltration operations," notes Vin Donovan, Vice President of Biopharm Process Solutions. "Users now have one platform for two process steps (TFF and Chromatography) with both systems sharing the same Smart Cart and software, thus streamlining the capital investment and learning curve while speeding their molecule to clinic."

The Smart Flexware® single-use flow path delivers equivalent or better performance to that of traditional stainless steel systems while maximizing system flexibility. Smart Flexware® assemblies are easy to install, reducing the risk of operator error and challenges typically associated with installing single-use flow paths. Additionally, the flow path significantly reduces dead-legs and moving parts, decreasing the risk of contamination to virtually zero.

EMD Millipore's Mobius® FlexReady Solutions provide the industry's only complete single-use process train, offering both upstream and downstream solutions that reduce the time and resources required for commercial protein manufacturing. Comprehensive services, including IQ/OQ, process qualification consultancy and first run support, ensure rapid implementation and optimized performance.