Bruker Autoflex Speed TOF/TOF MALDI with Smartbeam Laser

Bruker Autoflex Speed TOF/TOF MALDI with Smartbeam Laser

***This instrument was tested as far as we could. Unit powers on without errors but unable to connect to software due to PC wont boot. Unit has slight wear from normal use. (Worktable not included). See photos for details

Includes:

• Bruker Autoflex Speed Instrument
• HP Z4 Tower w/ Windows 10 & Autoflex I/O Card
• Dell Flat Panel Display

The autoflex™ speed series of MALDI based mass spectrometers has been designed to significantly increase productivity across a broad range of applications. With advances in performance and system capabilities, the autoflex speed series has the power, flexibility, and utility to be deployed in many analytical operations.

• Increased Efficiency in MALDI-TOF MS

Autoflex Speed TOF/TOF

• A high performance system providing all the capabilities of the autoflex series including MS/MS for detailed sample characterization.

The autoflex speed family of products encompasses numerous technology advances that provide researchers with:

• Unmatched analytical speed using smartbeam™-II, a 2 kilohertz laser and system electronics for intensive or
  high throughput applications. The MALDI customized smartbeam-II technology is exclusively developed, manufactured and maintained by Bruker for unsurpassed MALDI results.
• Expanded mass range capabilities to handle intact proteins and molecules such as large polymers.
• Superb broadband mass resolution and mass accuracy through proprietary PAN™ technology.
• Novel FlashDetector™ technology increases resolution and sensitivity and prevents signal saturation for
  complex samples.
• Minimized maintenance with IR laserbased self-cleaning MALDI Perpetual™ Ion Source, which improves system up-time and utility.
• Optimized software packages for a range of protein, peptide, and polymer analysis workflows.
  Redefined routine and generic applications.

One of the key benefits of the autoflex speed series is that these systems were designed and optimized to be easy to use, robust systems for both traditional MALDI mass spectrometer applications (protein, peptide, and polymer analysis) as well as cutting edge work (MALDI Imaging, glycan analysis). With this combination of performance and utility, the autoflex series is an excellent choice for a number of application areas including:

• Proteomics research
• Biomarker discovery
• Analysis of biotherapeutics
• Bioassay development and metabolite distribution
• Molecular histology/MALDI Imaging
• Polymer analysis
• Glycan and glycoprotein analysis
• Microorganism identification
• Intact Protein Sequencing

The Bruker Autoflex Speed is a MALDI-TOF/TOF mass spectrometer, and uses smartbeam™ II laser technology, with a repetition rate tunable from 1 to 2000 Hz, and an adjustable focus size from 10 μm to 80 μm. The instrument can be operated in linear mode with mass range of 500k, at very high sensitivity to measure large molecules. If higher resolution and mass accuracy is required, the instrument can be operated in reflectron mode. MS/MS experiments in LIFT mode, or using ISD processes. Typical experiments that can be carried out include rapid MALDI spot analysis, LC-MALDI analyses, and Tissue Imaging.

Increased efficiency in MALDI-TOF (/TOF)

• 2 kHz smartbeam-II laser technology enables ultra-high data acquisition speed.
• Laser focus diameters down to 10 µm for high spatial resolution imaging without pixel overlap.
• Wide mass range resolving power up to 26,000 due to proprietary PAN™ technology.
• FlashDetector™ combined with new 4 GHz digitizer provides 2 ppm mass accuracy for highest confidence.
• MALDI Perpetual™ Ion Source with laser-based self-cleaning in minutes. Its push-button concept for removing sample and matrix debris is indispensable for kHz operation.