Thermo Transcend LX-1 HPLC w/ TSQ Quantum Access MAX Mass Spectrometer System

Thermo Transcend LX-1 HPLC w/ TSQ Quantum Access MAX Mass Spectrometer System

**This unit has been tested to specifications and functionality. We have tested it as far as we are able. It will need 1 valve rotor and seal and the pumps will need minor preventative maintenance Unit has slight wear from normal use. Everything pictured included. See photos for details. Calibration and validation are separate, but please inquire with us for further details on extra services available.

Includes:

• TSQ Quantum Access MAX Mass Spectrometer
• Transcend Rheos 5600 Model 600 Pump (x2)
• Transcend Valve Interface Module Model 2303TX15K
• PAL HTS1-TM0-xt Autosampler w/ Cooling Stack 
• Electrospray (ESI) Ion Source

The speed of multichannel UHPLC

LC-MS users often waste valuable MS duty cycle on lengthy sample injection cycles, column washing, and column equilibration stages. The Thermo Scientific Transcend LX multichannel UHPLC systems eliminate wasted time by utilizing multiple LC channels interfaced with a single MS instrument for up to four-fold increase in throughput, depending on the configuration

The massive quantities of samples analyzed by liquid chromatography-mass spectrometry (LC MS/MS) in pharmaceutical research has driven the search for ways to increase throughput. However, increased throughput is only valuable when not sacrificing quality. Only the Thermo Scientific Transcend LX systems significantly increase throughput by multiplexing LC separations – without sacrificing selectivity or sensitivity and without requiring extensive training. Transcend™ LX series systems are designed to improve MS efficiency, productivity and throughput. 

• Accelerates results—quadruple mass spectrometer throughput
• Enhances productivity—analyze more samples per hour
• Improves efficiency—mass spectrometer idle < 4%
• Increases flexibility—4 different assays, simultaneously

Each LX system enables multiple assays to be run parallel into a single MS. This removes expensive downtime associated with setting up each individual assay. Setup is only required once – then you can run the method when needed. The built-in software intelligence ensures operation of multiple channels. If one channel goes down, it will automatically move the samples to another channel of the same method.

Flexible Upgrade Options
In most cases, existing HPLC/UHPLC equipment can be re-used when upgrading to an LX multiplexing system. In addition, all components of an existing LX-2 system
can be re-used when upgrading to an LX-4 system – to achieve four times the throughput of a single LC system. For complex samples, labs can upgrade to a TLX system which incorporates
TurboFlow™ automated online sample preparation technology, allowing direct injection of complex matrices, such as biological fluids and food. The TLX systems virtually eliminate up-front sample
preparation and deliver reliable analysis in a fraction of the time and cost required for offline methods.

The Thermo Scientific TSQ Quantum Access MAX triple stage quadrupole mass spectrometer is designed to meet the quantitative and qualitative challenges of a broad range of applications, including pharmaceutical, environmental, food safety, clinical research, and forensics. Based on
the widely used TSQ Quantum system, it sets the benchmark for sensitivity in its class, and provides unmatched analytical specificity.

Capabilities such as Highly Selective Reaction Monitoring (H-SRM) and high Field Asymmetric waveform Ion Mobility Spectrometry (FAIMS) are available on the TSQ Quantum Access MAX™. Innovative technology such as Quantitation-Enhanced Data-Dependent MS/MS (QED-MS/MS)
makes structural confirmation and quantitation easy, facilitating metabolite ID or multiresidue screens. Also, standard is the new Reversed Energy Ramp (RER) scan, which ensures library-searchable, fragment-rich MS/MS spectra are produced routinely

• Up to 3,000 definable, timed SRMs and fast 25 MS positive/negative switching improve productivity.
• Quantitation-enhanced data-dependent MS/MS (QED-MS/MS) provides simultaneous compound confirmation and quantification.
• High-resolution selected reaction monitoring (H-SRM) with 2 MS dwell times enables quantification of hundreds of compounds in a single run.
• Mass range of 10–3000 m/z allows analysis of small molecules and intact proteins.
• Zero-crosstalk collision cell eliminates false positives.
• Self-cleaning Ion Max API source heater with automatic source recognition simplifies use and increases reliability.