Cynvenio Liquid Biop Automated Rare Cell Isolate CLEARANCE! As-Is

The LiquidBiopsy Platform for rare cell isolation uses a comprehensive sample-to-sequence solution on a single blood sample for analysis of circulating tumor cells (CTCs), cell-free DNA (cfDNA), and germline DNA in less than 48 hours. The LiquidBiopsy Platform automates CTC isolation and is optimized for downstream molecular characterization by next-generation sequencing (NGS) and expression analysis.

Manufacture Specification 

• Automated processes- Flow cell priming, blood sample loading, target cell isolation, immunofluorescence labeling of captured cells
• Sample format- Whole blood
• Sample input volume- User definable, 2 mL–7.5 mL
• Sample throughput-  5 mL/hr, 4 channels: 1 rare cell flow cell per channel (4 samples/rare cell isolations processed concurrently), User can select how many samples to process for each run (up to 4)
• Capture reagents- Standard capture reagents supported include antibodies against EpCAM, Trop2, Her2, MUC1/CD227
• Isolation flow cells (IFC)- The IFC is compatible with standard microscopy and imaging platforms for downstream cell  characterization of targets that have been isolated and stained on the LiquidBiopsyTM Platform. Dimensions: 0.93 in. x 2.87 in. (2.36 cm x 7.29 cm)
• On-platform assay time- 1.5–3 hr, depending on sample volume
• Working environment- For indoor use only. Temperature: 50–95°F (10–35°C); humidity: 5%–95% (noncondensing) Clearances: 6 in. (15.25 cm) on all sides
• Instrument computer hardware- Siemens® SIMATIC® ET 200S programmable logic controller (PLC)